Jack Carty will make when Ireland face hosts Japan in Saturday’s World Cup clash in 22, his second Test start.
The Connacht fly-half will pilot the backline of Ireland with boss Joe Schmidt to hazard Johnny Sexton, who has nursed a slight leg issue.
Joey Carbery is inserted again after ankle ligament trouble and requires a seat.
Carty impressed the bench in the closing stages of Ireland’s 27-3 win over Scotland in Yokohama, also now the playmaker has the opportunity to impose his existence on this Earth Cup.
Sexton ceded responsibilities to Conor Murray also has been pulled following his side try.
The Leinster star did not train completely on Tuesday, and Schmidt has chosen not to take any chances.
Rob Kearney and Keith Earls return to the starting XV with Ireland making four changes to their beginning line-up, getting missed the Pool A opener against Scotland because of trauma.
Kearney has shaken off his wing complaint and Earls is currently over his own thigh concern.
While all the head injury tests were completed by Bundee Aki and returned to complete training, head coach Schmidt opted not to risk the battering ram centre of Connacht. Chris Farrell starts with the Munster man in Japan in fine form and fettle.
Jack Conan was expected to begin from the back-row but picked up an injury in practice which Peter O’Mahony was pressed back into service in flanker.
Munster star O’Mahony neglected a Head Injury Assessment (HIA) at Saturday’s win over Scotland, but immediately passed all the necessary tests and returned to complete training on Tuesday.
Schmidt has ended up fielding the identical pack that dimmed the Scots, together using Rory Best as captain flanked in the front-row by Cian Healy and Tadhg Furlong.
Iain Henderson and james Ryan will keep as Ireland flexed considerable set-piece muscle from the Scotland of Gregor Townsend, their venture that went in Yokohama.
Ireland: 15 Rob Kearney, 14 Keith Earls, 13 Garry Ringrose, 12 Chris Farrell, 11 Jacob Stockdale, 10 Jack Carty, 9 Conor Murray, 1 Cian Healy, 2 Rory Best (c), 3 Tadhg Furlong, 4 Iain Henderson, 5 James Ryan, 6 Peter O’Mahony, 7 Josh Van der Flier, 8 CJ Stander
Replacements: 16 Sean Cronin, 17 David Kilcoyne, 18 Andrew Porter, 19 Tadgh Beirne, 20 Rhys Ruddock, 21 Luke McGrath, 22 Joey Carbery, 23 Jordan Larmour
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