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Triamterene is awater pilldiureticthat works in your kidneys to increase the amount of urine you makeThis helps your body get rid of extra waterThis medication is used to decrease swellingedemacaused by conditions such as cancercongestive heart failureliver diseaseand kidney diseaseThis effect can help your kidneys work better and lessen symptoms such as trouble breathing and swelling in your anklesfeethandsor belly.

In studies conducted under the auspices of the National Toxicology Programgroups of rats were fed diets containing 0150300 or 600 ppm triamtereneand groups of mice were fed diets containing 0100200 or 400 ppm triamtereneMale and female rats exposed to the highest tested concentration received triamterene at about 25 and 30 mg/kg/dayrespectivelyMale and female mice exposed to the highest tested concentration received triamterene at about 45 and 60 mg/kg/dayrespectively.

MAXZIDE should be used with caution in patients with impaired hepatic function or progressive liver diseasesince minor alterations of fluid and electrolyte balance may precipitate hepatic coma.

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