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The plasma protein binding of danazol is unknown.

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Information about Danazol.

Keep all appointments with your doctor and the laboratoryYour doctor may order certain lab tests before and during your treatment to check your body’s response to danazol.

Danazol has a multitude of effects on the bodySome of these effects combine to produce high levels of androgen and low levels of oestrogen in the bodyThis hormonal environment stops menstruation and suppresses the growth of endometrial implantscausing them to degenerate1,2

4A wide range of actions on plasma proteinsincluding increasing prothrombinplasminogenantithrombin IIIalpha-2 macroglobulinC1 esterase inhibitorand erythropoietin and reducing fibrinogenthyroid binding and sex hormone binding globulinsDanazol increases the proportion and concentration of testosterone carried unbound in plasma.

Danazol is indicated for the prevention of attacks of angioedema of all typescutaneousabdominallaryngealin males and females.

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however, these studies did not specify the dose and the duration of danazol treatment, or the details of the patient follow-up performed to detect erythrocytosis.

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