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In patients with gastroesophageal reflux and low LESPlower esophageal sphincter pressuresingle oral doses of metoclopramide produce dose-related increases in LESPEffects begin at about 5 mg and increase through 20 mgthe largest dose testedThe increase in LESP from a 5 mg dose lasts about 45 minutes and that of 20 mg lasts between 2 and 3 hoursIncreased rate of stomach emptying has been observed with single oral doses of 10 mg.

Metoclopramide itself may suppressor partially suppressthe signs of TDthereby masking the underlying disease processThe effect of this symptomatic suppression upon the long-term course of TD is unknownThereforemetoclopramide should not be used for the symptomatic control of TD.

Metoclopramide itself may suppressor partially suppressthe signs of TDthereby masking the underlying disease processThe effect of this symptomatic suppression upon the long-term course of TD is unknownThereforemetoclopramide should not be used for the symptomatic control of TD.

Metoclopramide may impair the mental and/or physical abilities required for the performance of hazardous tasks such as operating machinery or driving a motor vehicleThe ambulatory patient should be cautioned accordingly.

There are insufficient reliable data to conclude whether the pharmacokinetics of metoclopramide in adults and the pediatric population are similarAlthough there are insufficient data to support the efficacy of metoclopramide in pediatric patients with symptomatic gastroesophageal refluxGERor cancer chemotherapy-related nausea and vomitingits pharmacokinetics have been studied in these patient populations.

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gerd and while reglan is pretty much under control with prilosec and gaviscon, i still seem to have some long-lasting negative side bloomers.

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